Papillary carcinoma is the most common among malignant tumors of the thyroid (60-70% of all thyroid carcinomas). Women are affected two to three times more often than men. It is more common in young people, but in the elderly has increased malignancy.
It is more common in patients with a history of exposure to radiation and spreads through the lymphatic. You may find lateral aberrant thyroid remnants that are actually occult metastases with a benign histological appearance. These well-differentiated carcinomas may be TSH-dependent and may develop in the context of goiters secondary to Hashimoto’s thyroiditis. Many papillary carcinomas contain follicular elements, but this does not change the basic biology of the tumor. (more…)