Gestational Diabetes
Monday, November 16th, 2009Definition:Any that alteration in the metabolism of carbohydrates that are first detected during pregnancy.
• Inadequate adaptation to insulin resistance that occurs in pregnancy.
• Includes a small group of pregnant women with diabetes mellitus type I or II not previously diagnosed.

• The association of diabetes and pregnancy has a frequency between 1 and 5%, varying in relation to the population analyzed by geographic area and the diagnostic criteria used
• Represents about 90% of pregnant women with diabetes and high risk obstetric conditions if not diagnosed or not treated properly
Physiology
First Quarter:
• There is hyperplasia of cls. pancreatic beta and increased sensitivity of these to glucose, the effect of estrogen and progesterone
• Increased sensitivity to insulin action at peripheral level
Consequence: Decreased fasting and postprandial glycemia away
Pathophysiologic
• High resistance to insulin of the same magnitude in normal pregnant women and diabetes, but is three times greater than that observed outside pregnancy.
• Predominantly located in the muscle tissue and is mediated by the cellular effects produced by placental hormones, especially placental lactogen and free cortisol.
Gestational Diabetes
It is usually asymptomatic disease and therefore must be sought dirigidamente. (more…)
