Archive for the ‘Pharmacology’ Category

Five facts about birth control pills

Saturday, May 28th, 2011

Asking, in any case, always represents a healthy exercise. Often happens that, whether out of shame or by fear to leave in evidence our intellectual weaknesses, men restrict the questions, too bad, therefore while itself not the ignorance be asked will continue there in its place.

birth control pills

All about the pill
Especially in the case of health, it is always important to clear any unknown. Birth control pills serve as an example of the risk to be enclosed in a taboo one: there are few women, for misuses of them have suffered serious problems from pregnancy to some type of poisoning. Therefore, from here, we present five questions, and its answers, on, just the pill.

Are there any possibility of having infertility if treatment is stopped?
Impossible. The pills can leave at the time that you want and, among the factors that may occur, there is nothing like that. The chance of infertility due to abandonment of the drug is not covered by any such medication. (more…)

Keys of Chinese Medicine

Tuesday, November 9th, 2010

According to the principles of Chinese medicine, a poor flow of energy can jeopardize the body’s balance. Since the acupuncture, the Qi Gong, these therapeutic disciplines are intended to restore harmony within the energy flows.

In China, the medicine is transmitted from generation to generation. The greater the number of previous generations devoted to medicine, the greater the prestige and respect received. Chinese medicine has over 5000 years and is particularly interested in communicating different physiological functions.

Branches of knowledge
These are closely connected the each other through a flow of energy called “Chi”. This energy is the basis of Chinese medical principle. Under this principle, the disease is the result of a crash or some energetic imbalances. (more…)

Drug-receptor Interactions

Monday, May 10th, 2010

Few drugs, if any, have absolute specificity, but most features on selectivity, eg., Atropine inhibits the action of acetylcholine on smooth muscle and exocrine glands, but not the skeletal muscle. The selective action of these drugs is due to their physical-chemical bond with cellular components known as receptors. The receptors are physiological molecules involved in transmitting chemical signals between a cell and another and within cells. A molecule that binds to a receptor is defined ligand. When a ligand (hormone, neurotransmitter, drug or intracellular messenger exogenous) combines with a receptor cell function is changed, each ligand can interact with multiple receptor subtypes. The receptors activated directly or indirectly regulate cellular biochemical processes (eg., Ion conductance, protein phosphorylation, transcription of DNA). In many cases, the receptors located within the cell membrane are coupled through the guanine nucleotide binding proteins (G proteins) with different effector systems involving molecules that act as intracellular second messengers.

The receptors are dynamic structures, affected by both external factors and by intracellular regulatory mechanisms. The up-regulation and down-regulation of receptors relate phenomena of adaptation to drugs which have important clinical implications (desensitization, tolerance, acquired resistance, hypersensitivity to suspension).

The specific regions of macromolecules molecular receptor which binds the ligand recognition sites are called. A drug may interact at the same site which interacts with an endogenous agonist (hormone or neurotransmitter) or at a different site. Agonists that bind to adjacent sites or different allosteric agonists are sometimes called. The drugs are also linked in a non-specific, ie not at the molecular features of sites like receptors (eg., Plasma proteins). (more…)

Prescription Drug Abuse

Wednesday, April 7th, 2010

Some people experiment with prescription drugs because they believe that will help even more fun, lose weight to fit into a certain group and even to study better. Prescription drugs can be achieved more easily than illicit drugs: it is likely that a family member or friend has a prescription. But in some cases, prescription drugs are sold on the street like other illegal drugs.

But prescription drugs are only safe for people who have been prescribed. This is because a doctor has examined these people and know they will not have adverse drug reactions. The doctor also told them exactly how to take the medication and what to avoid while you take: as alcohol, tobacco or other drugs.

Canadian Prescription drugs that are used most often are classified into three categories:

Opioides
Examples: oxycodone (OxyContin), hydrocodone (Vicodin) and meperidine (Demerol).
Medical uses: Opioids are used to treat pain or relieve coughs or diarrhea.
How they work: Opioides attach to opioid receptors in the central nervous system (brain and spinal cord) and prevent the brain from receiving pain messages. (more…)

General pharmacology

Tuesday, November 10th, 2009

Medication: Any substance or combination of substances for treating or preventing disease in human, as well as product out that can be administered to humans or animals to establish a diagnosis or to restoring, correcting or modify their functions.
Whatever its form combines a drug:
An active (therapeutic)
A vehicle (no action against the disease, support the active ingredient)
With an adjuvant (facilitates the implementation, administration, or retention of the drug).
The origins of drugs:
A plant (herbal)
Ä animal (opotherapy)
Ä mineral (trace element, mercury, …)
Ä microbial origin (antibiotics, vaccines, …)
Ä synthetic origin (chemotherapy, …)
Ä biotechnological origin (laboratory, biogenetic engineering, …). (more…)

Steroids

Tuesday, November 10th, 2009

Mechanisms of Action
Steroids alter the synthesis of proteins therefore alter:

  • Chemotaxis,
  • Metabolism
  • Expression (hormones, mediators).

Pharmacological Actions

Cortisol (hormone)
Corticosteroid (drug)
Anti-inflammatory effects,
Provide glucose to the brain,
Effects immuno-modulators,
Effects on carbohydrate
Effects on carbohydrate
Effects on lipids,
Effects on lipids,
Effects on protein
Effects on protein
Metabolic,
Effects on the brain
Cardiac effects.

(more…)

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