Fighting Diabetes (excess blood glucose, for various reasons) remains a major unresolved for medicine. Yes, there are drugs, but realistically are only “patches “to try to alleviate the problem, for the moment we cannot cure it completely and utterly. There are pills (such as metformin) or injections (intravenous insulin), but are daily treatments, of even several doses per day and very annoying. The question is, is there any way to treat this disease to end it? Perhaps, little by little, we’re approaching it.
A new treatment that takes years trying, with limited success, is the “cellular reprogramming “. This means revive malfunctioning cells in diabetics (beta cells of the pancreas, whose function is to produce insulin, and who fail partially or completely depending on the type of diabetes that suffers). But the new approach goes further, including other cells, alpha cells in the same equation treatment.
According to the study, published in the Journal of Clinical Investigation, human cells such as mouse cells treated with compounds that modify the material of the cell nuclei (chromatin) would be able to express and activate the genes of beta cells in the alpha cells. That is, if in a particular location it does not work (in beta cells), why not make it work in other cells? (Alpha cells). The treatment would be directed to patients with type 2 diabetes. (more…)