Objectives:
Prevention: infections from the microbial flora of the skin and mucous membranes.
Treat: so healing wounds, burns and skin infection.
It all preventive measures to:

  • to destroy micro-organism
  • does not introduce other

=> Without damaging the tissue.
The antiseptic applies to 2 types of environments:
Living Environments => antiseptic
Midfielder inert => disinfectant.
Disinfection
Used to describe the elimination of micro-organism in order to prevent infection.


Antisepsis
Restricted to treatment of infection or colonization constituted.
Antiseptic:

  • product used in antisepsis in defined conditions,
  • subject to drug marketing authorizations subject to medical prescription as well as antibiotics.

Effects and spectra of activity:
Bactericidal: action of lethal bacteria.
Sporicidal: Destroys bacterial spores are more resistant than vegetative forms.
Fongicide : lethal action on fungal cells.
Virucidal: Capable of destroying the virus particles.


Modes of action, not always well known:
3 types of mechanisms:

  • irreversible alteration of the cell membrane of micro-organism
  • inhibition of enzymes essential to the life of the micro-organism
  • denaturation of structural proteins or nucleic acids of micro-organism.

Activity: influences
concentration
temperature
pH
proteins.
Terms of Use:
Choosing an antiseptic:

  • based on matching benefits and risks associated with product
  • must meet the recommendations for use of manufacturer:
    • active concentration,
    • contact time,
    • need to operate on wet or dry skin,
    • existence of conflict or antagonism.

Classification of antiseptics:

  • Quaternary ammonium compounds,
  • Biguanides (chlorhexidine)
  • phelon compounds,
  • Carbonilides (Tricloban)
  • Alcohols,
  • Halogenated (chlorinated Halogenated; Halogenated iodine)
  • oxidizers,
  • acids,
  • Metal derivatives (Organo-mercury)
  • Dyes,
  • Misc.
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